Bruno Frediani Selected Research

6- amino- 1- hydroxyhexane- 1,1- diphosphonate

10/2022	Intravenous neridronate is effective in regional migratory osteoporosis.
9/2022	Efficacy of intravenous neridronate in transient osteoporosis of the hip.
1/2021	Intramuscular neridronate for the treatment of complex regional pain syndrome type 1: a randomized, double-blind, placebo-controlled study.
11/2008	Intramuscular neridronate in postmenopausal women with low bone mineral density.

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Bruno Frediani Research Topics

Disease

23	Uveitis 12/2021 - 01/2012
14	Rheumatoid Arthritis 10/2021 - 06/2004
12	Inflammation (Inflammations) 10/2022 - 05/2012
11	Osteoporosis 10/2022 - 07/2006
8	Fever (Fevers) 10/2022 - 07/2012
8	COVID-19 10/2022 - 01/2020
8	Necrosis 07/2020 - 05/2013
7	Vasculitis (Vasculitides) 01/2022 - 01/2017
7	autosomal dominant familial Periodic fever 01/2021 - 11/2012
6	Pain (Aches) 09/2022 - 05/2015
5	Amyloidosis 01/2020 - 09/2013
4	Scleritis (Episcleritis) 01/2022 - 10/2017
4	Macular Edema 03/2021 - 01/2017
4	Retinal Vasculitis 03/2021 - 01/2017
4	Knee Osteoarthritis 01/2021 - 08/2018
4	Axial Spondyloarthritis 01/2021 - 07/2018
4	Psoriatic Arthritis 01/2021 - 01/2013
4	Ankylosing Spondylitis 07/2018 - 01/2014
4	Alkaptonuria 07/2017 - 09/2013
4	Bone Resorption 03/2013 - 01/2009
3	Abdominal Pain (Pain, Abdominal) 10/2022 - 11/2012
3	Overweight 05/2022 - 01/2021
3	Interstitial Lung Diseases (Interstitial Lung Disease) 02/2022 - 03/2021
3	Anterior Uveitis 12/2021 - 11/2016
3	Edema (Dropsy) 04/2021 - 03/2020
3	Complex Regional Pain Syndromes 01/2021 - 05/2015
3	Panuveitis 01/2020 - 01/2019
3	Behcet Syndrome (Behcet's Syndrome) 01/2020 - 07/2015
3	Cryopyrin-Associated Periodic Syndromes 06/2018 - 01/2013
3	Mevalonate Kinase Deficiency 06/2018 - 01/2013
3	Rheumatic Diseases (Rheumatism) 12/2016 - 10/2016
3	Arthritis (Polyarthritis) 05/2015 - 06/2011
2	Exanthema (Rash) 10/2022 - 11/2012
2	Arthralgia (Joint Pain) 10/2022 - 11/2012
2	Myositis (Idiopathic Inflammatory Myopathies) 03/2022 - 01/2021
2	Sarcoidosis (Schaumann Disease) 02/2022 - 01/2021
2	Fibrosis (Cirrhosis) 01/2022 - 09/2020
2	Giant Cell Arteritis (Horton Disease) 01/2022 - 01/2020
2	Serositis 01/2021 - 11/2012
2	Musculoskeletal Diseases (Musculoskeletal Disease) 01/2021 - 01/2020
2	Chronic Disease (Chronic Diseases) 01/2021 - 06/2014
2	Back Pain (Backache) 01/2021 - 01/2009
2	Proteinuria 01/2021 - 01/2020
2	Neoplasms (Cancer) 12/2020 - 06/2006
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 12/2020 - 01/2020
2	Synovitis 01/2020 - 11/2019
2	Adult-Onset Still's Disease 01/2020 - 01/2020
2	Familial Mediterranean Fever (Periodic Disease) 06/2018 - 01/2013
2	Blau syndrome 10/2017 - 01/2013

Drug/Important Bio-Agent (IBA)

15	Biological ProductsIBA 12/2021 - 01/2014
14	Pharmaceutical PreparationsIBA 03/2021 - 01/2009
13	Adalimumab (Humira)FDA Link 01/2022 - 11/2013
10	Adrenal Cortex Hormones (Corticosteroids)IBA 02/2019 - 05/2012
9	Biomarkers (Surrogate Marker)IBA 10/2022 - 06/2004
9	Antirheumatic Agents (DMARD)IBA 10/2021 - 01/2017
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2020 - 11/2012
9	InterleukinsIBA 02/2020 - 05/2013
9	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2020 - 07/2012
8	Diphosphonates (Bisphosphonates)IBA 08/2018 - 10/2004
7	GlucocorticoidsIBA 01/2022 - 07/2006
7	Interleukin-1 (Interleukin 1)IBA 01/2021 - 01/2017
7	Infliximab (Remicade)FDA Link 02/2019 - 11/2013
6	Biosimilar PharmaceuticalsIBA 12/2021 - 10/2016
6	CytokinesIBA 01/2021 - 09/2013
6	Clodronic Acid (Clodronate)IBA 03/2020 - 01/2009
6	SteroidsIBA 01/2020 - 01/2017
5	InflammasomesIBA 01/2021 - 01/2013
5	Tumor Necrosis Factor InhibitorsIBA 01/2020 - 05/2013
4	6- amino- 1- hydroxyhexane- 1,1- diphosphonateIBA 10/2022 - 11/2008
4	tocilizumab (atlizumab)FDA Link 10/2022 - 09/2013
4	C-Reactive ProteinIBA 05/2022 - 07/2018
4	Interleukin-6 (Interleukin 6)IBA 01/2021 - 03/2013
4	Etanercept (Enbrel)FDA Link 01/2020 - 11/2013
4	canakinumab FDA Link 01/2020 - 04/2015
4	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2019 - 01/2013
4	Fluorescein (Funduscein)FDA LinkGeneric 07/2017 - 01/2017
3	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 02/2022 - 03/2021
3	Serum Amyloid A Protein (Serum Amyloid A)IBA 01/2021 - 09/2013
3	Certolizumab Pegol FDA Link 01/2021 - 11/2017
3	golimumab FDA Link 01/2021 - 01/2019
3	Colchicine FDA LinkGeneric 01/2020 - 07/2012
3	Immunosuppressive Agents (Immunosuppressants)IBA 08/2018 - 07/2012
2	Rituximab (Mabthera)FDA Link 12/2022 - 01/2021
2	Ferritins (Ferritin)IBA 10/2022 - 01/2021
2	Methylprednisolone FDA LinkGeneric 10/2022 - 06/2004
2	Alkaline PhosphataseIBA 01/2022 - 06/2004
2	Parathyroid Hormone (Parathormone)IBA 01/2022 - 06/2011
2	baricitinibIBA 07/2021 - 09/2020
2	Methotrexate (Mexate)FDA LinkGeneric 07/2021 - 01/2013
2	Hyaluronic Acid (Hyaluronan)IBA 01/2021 - 01/2020
2	ruxolitinibIBA 12/2020 - 01/2020
2	AntibodiesIBA 07/2020 - 01/2017
2	secukinumabIBA 01/2020 - 07/2018
2	Monoclonal AntibodiesIBA 03/2019 - 07/2017
2	NitrogenIBA 08/2018 - 01/2009
2	Antigen-Antibody Complex (Immune Complex)IBA 01/2018 - 01/2015

Therapy/Procedure

20	Therapeutics 01/2021 - 06/2004
5	Biological Therapy 12/2021 - 01/2018
2	Precision Medicine 02/2022 - 12/2021
2	Duration of Therapy 01/2019 - 06/2018